Anticorps M6PR (cation independent)

21 produits

M6PR (cation independent) est un gène codé par le symbole IGF2R. Communément appelé aussi: Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; IGF2R; MPRI. M6PR (cation independent) a une masse de 274.38kDa et une longueur d'acide aminé de 2491.

Nous proposons 21 des anticorps contre M6PR (cation independent), élevé dans Lapin et Souris, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF, Cytométrie en Flux et IP avec des échantillons dérivés de Humain, Souris, Rat et Primates.

Informations sur les Gènes et les Protéines

Résumé UniProt
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Résumé Entrez
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).
Similitudes de séquence
Belongs to the MRL1/IGF2R family.
Localisation cellulaire
Lysosome membrane.

Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface.
Western Blot - Anti-CD222 Antibody [MEM-238] (A85552) - Antibodies.com
Voir le roduitTaille d'Essai de 10µg
Western Blot - Anti-M6PR (cation independent) Antibody (A89200) - Antibodies.com
(4)
Western Blot - Anti-M6PR (cation independent) Antibody [ARC0263] (A308985) - Antibodies.com
(4)
Immunofluorescence - Anti-IGF2R Antibody (B1051) - Antibodies.com
(2)
Voir le roduitTaille d'Essai de 10µg
Immunofluorescence - Anti-IGF2R Antibody (B1211) - Antibodies.com
(2)
Voir le roduitTaille d'Essai de 10µg
ELISA - Anti-IGF2R (phospho Ser2409) Antibody (P12-1119) - Antibodies.com
(2)
Voir le roduitTaille d'Essai de 10µg
Immunohistochemistry - Anti-IGF2R (phospho Ser2409) Antibody (A1211) - Antibodies.com
(2)
Voir le roduitTaille d'Essai de 10µg
Flow Cytometry - Anti-CD222 Antibody [MEM-238] (PE) (A85551) - Antibodies.com
Flow Cytometry - Anti-CD222 Antibody [MEM-238] (FITC) (A85549) - Antibodies.com
Flow Cytometry - Anti-CD222 Antibody [MEM-238] (Biotin) (A86836) - Antibodies.com
Flow Cytometry - Anti-CD222 Antibody [MEM-240] (A86835) - Antibodies.com
Voir le roduitTaille d'Essai de 10µg
Western Blot - Anti-IGF2R Antibody (C30461) - Antibodies.com
(2)
Voir le roduitTaille d'Essai de 10µg
Flow Cytometry - Anti-CD222 Antibody [MEM-240] (PE) (A86837) - Antibodies.com
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Anti-M6PR Antibody from Bioworld Technology (BS8108) - Antibodies.com
(3)
Western blot - IGF2R (Phospho-Ser2409) Antibody from Signalway Antibody (11708) - Antibodies.com
(2)
IGF2R Antibody from Signalway Antibody (37644) - Antibodies.com
(2)
Western blot - IGF2R (Phospho-Ser2484) Antibody from Signalway Antibody (12443) - Antibodies.com
M6PR Antibody from Signalway Antibody (43050) - Antibodies.com
(2)

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