Kallikrein 5 est un gène codé par le symbole KLK5. Communément appelé aussi: Kallikrein-5; Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme; KLK5; SCTE. Kallikrein 5 a une masse de 32.02kDa et une longueur d'acide aminé de 293.
Nous proposons 23 des anticorps contre Kallikrein 5, élevé dans Lapin, Souris, Chèvre et Human, qui sont appropriés pour le WB, IHC et ELISA avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
May be involved in desquamation.
Résumé Entrez
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
Spécificité tissulaire
Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin.
Similitudes de séquence
Belongs to the peptidase S1 family. Kallikrein subfamily.
Localisation cellulaire
Secreted.
