intestinal FABP est un gène codé par le symbole FABP2. Communément appelé aussi: Fatty acid-binding protein, intestinal; Fatty acid-binding protein 2; Intestinal-type fatty acid-binding protein; I-FABP; FABP2; FABPI. intestinal FABP a une masse de 15.21kDa et une longueur d'acide aminé de 132.
Nous proposons 13 des anticorps contre intestinal FABP, élevé dans Lapin, Souris et Chèvre, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF et Cytométrie en Flux avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
Résumé Entrez
The protein encoded by this gene is an intracellular fatty acid-binding protein that participates in the uptake, intracellular metabolism, and transport of long-chain fatty acids. The encoded protein is also involved in the modulation of cell growth and proliferation. This protein binds saturated long-chain fatty acids with high affinity, and may act as a lipid sensor to maintain energy homeostasis.
Spécificité tissulaire
Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.
Similitudes de séquence
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Localisation cellulaire
Cytoplasm.
