Interferon beta est un gène codé par le symbole IFNB1. Communément appelé aussi: IFN-beta; Fibroblast interferon; IFNB1; IFB; IFNB. Interferon beta a une masse de 22.29kDa et une longueur d'acide aminé de 187.
Nous proposons 11 des anticorps contre Interferon beta, élevé dans Lapin, Souris et Chèvre, qui sont appropriés pour le WB, IHC et ELISA avec des échantillons dérivés de Humain, Souris et Bovin.
Informations sur les Gènes et les Protéines
Résumé UniProt
Has antiviral, antibacterial and anticancer activities.
Résumé Entrez
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
Similitudes de séquence
Belongs to the alpha/beta interferon family.
Localisation cellulaire
Secreted.
