IL9R est un gène codé par le symbole IL9R. Communément appelé aussi: Interleukin-9 receptor; IL-9 receptor. IL9R a une masse de 57.15kDa et une longueur d'acide aminé de 521.
Nous proposons 10 des anticorps contre IL9R, élevé dans Lapin et Souris, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF et Cytométrie en Flux avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
This is a receptor for interleukin-9.
Résumé Entrez
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
Similitudes de séquence
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Localisation cellulaire
Cell membrane. Secreted.
