HOXB6 est un gène codé par le symbole HOXB6. Communément appelé aussi: Homeobox protein Hox-B6; Homeobox protein Hox-2.2; Homeobox protein Hox-2B; Homeobox protein Hu-2; HOX2B. HOXB6 a une masse de 25.43kDa et une longueur d'acide aminé de 224.
Nous proposons 2 des anticorps contre HOXB6, élevé dans Lapin, qui sont appropriés pour le WB et IHC avec des échantillons dérivés de Humain et Souris.
Informations sur les Gènes et les Protéines
Résumé UniProt
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Résumé Entrez
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.
Similitudes de séquence
Belongs to the Antp homeobox family.
Localisation cellulaire
Nucleus.
