Cyclin G est un gène codé par le symbole CCNG1. D'autres noms incluent: Cyclin-G1; Cyclin-G; CCNG1; CCNG; CYCG1. Cyclin G a une masse de 34.07kDa et une longueur d'acide aminé de 295.
Nous proposons 6 des anticorps contre Cyclin G, élevé dans Lapin, qui sont appropriés pour le WB, IHC, ELISA et ICC/IF avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).
Résumé Entrez
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.
Spécificité tissulaire
High levels in skeletal muscle, ovary, kidney and colon.
Similitudes de séquence
Belongs to the cyclin family. Cyclin G subfamily.
Localisation cellulaire
Nucleus.
DNA replication foci after DNA damage.
