CTBP2 est un gène codé par le symbole CTBP2. Il est également connu sous le nom de C-terminal-binding protein 2. CTBP2 a une masse de 48.95kDa et une longueur d'acide aminé de 445.
Nous proposons 14 des anticorps contre CTBP2, élevé dans Lapin et Souris, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF, Cytométrie en Flux et IP avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity).
Résumé Entrez
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.
Spécificité tissulaire
Ubiquitous. Highest levels in heart, skeletal muscle, and pancreas.
Similitudes de séquence
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Localisation cellulaire
Nucleus. Cell junction > Synapse.
