Cadherin 16 est un gène codé par le symbole CDH16. D'autres noms incluent: Cadherin-16; Kidney-specific cadherin; Ksp-cadherin; CDH16. Cadherin 16 a une masse de 89.92kDa et une longueur d'acide aminé de 829.
Nous proposons 32 des anticorps contre Cadherin 16, élevé dans Lapin et Souris, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF et Cytométrie en Flux avec des échantillons dérivés de Humain, Souris, Rat, Lapin et Canin.
Informations sur les Gènes et les Protéines
Résumé UniProt
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Résumé Entrez
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Spécificité tissulaire
Kidney specific.
Localisation cellulaire
Cell membrane.
