Anticorps BMP15

6 produits

BMP15 est un gène codé par le symbole BMP15. D'autres noms incluent: Bone morphogenetic protein 15; BMP-15; Growth/differentiation factor 9B; GDF-9B; GDF9B. BMP15 a une masse de 45.06kDa, une longueur d'acide aminé de 392, et est impliqué dans les maladies: Ovarian dysgenesis 2; Premature ovarian failure 4.

Nous proposons 6 des anticorps contre BMP15, élevé dans Lapin et Souris, qui sont appropriés pour le WB, IHC et ELISA avec des échantillons dérivés de Humain, Souris et Rat.

Informations sur les Gènes et les Protéines

Résumé UniProt
May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.
Résumé Entrez
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure.
Implication dans la maladie
Ovarian dysgenesis 2: A disorder characterized by lack of spontaneous pubertal development, primary amenorrhea, uterine hypoplasia, and hypergonadotropic hypogonadism as a result of streak gonads.

Premature ovarian failure 4: An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol.
Similitudes de séquence
Belongs to the TGF-beta family.
Localisation cellulaire
Secreted.
Liens de base de données
Western Blot - Anti-BMP15 Antibody (C30665) - Antibodies.com
(4)
Voir le roduitTaille d'Essai de 10µg
Western Blot - Anti-BMP15 Antibody [ARC0907] (A306596) - Antibodies.com
(2)
SDS-PAGE - Anti-BMP15 Antibody [BMP15/4263] - BSA and Azide free (A253700) - Antibodies.com
SDS-PAGE - Anti-BMP15 Antibody [BMP15/4263] (A250520) - Antibodies.com
Western blot - BMP15 Antibody from Signalway Antibody (25504) - Antibodies.com
BMP15 Antibody from Signalway Antibody (36288) - Antibodies.com
(2)

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