alpha Internexin est un gène codé par le symbole INA. D'autres noms incluent: Alpha-internexin; Alpha-Inx; 66 kDa neurofilament protein; NF-66; Neurofilament 5; INA; NEF5. alpha Internexin a une masse de 55.39kDa et une longueur d'acide aminé de 499.
Nous proposons 9 des anticorps contre alpha Internexin, élevé dans Lapin, Souris et Poulet, qui sont appropriés pour le WB, IHC et ICC/IF avec des échantillons dérivés de Humain, Souris, Rat, Bovin, Porcin, Félin et Cheval.
Informations sur les Gènes et les Protéines
Résumé UniProt
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity).
Résumé Entrez
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.
Spécificité tissulaire
Found predominantly in adult CNS.
Similitudes de séquence
Belongs to the intermediate filament family.
Modification post-traductionnelle
O-glycosylated.
