ADFP est un gène codé par le symbole PLIN2. D'autres noms incluent: Perilipin-2; Adipophilin; Adipose differentiation-related protein; ADRP; PLIN2. ADFP a une masse de 48.08kDa et une longueur d'acide aminé de 437.
Nous proposons 17 des anticorps contre ADFP, élevé dans Lapin et Souris, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF et Cytométrie en Flux avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
May be involved in development and maintenance of adipose tissue.
Résumé Entrez
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.
Spécificité tissulaire
Milk lipid globules.
Similitudes de séquence
Belongs to the perilipin family.
Modification post-traductionnelle
Acylated; primarily with C14, C16 and C18 fatty acids.
Localisation cellulaire
Membrane. Lipid droplet.
