Substance P est un gène codé par le symbole TAC1. Il est également connu sous le nom de: Protachykinin-1; PPT; TAC1; NKA; NKNA; TAC2. Substance P a une masse de 15kDa et une longueur d'acide aminé de 129.
Nous proposons 7 Substance P kits ELISA pour la détection qualitative ou quantitative de Substance P à partir d'échantillons Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Résumé Entrez
This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene.
Similitudes de séquence
Belongs to the tachykinin family.
Modification post-traductionnelle
The substance P form is cleaved at Pro-59 by the prolyl endopeptidase FAP (seprase) activity (in vitro).
Localisation cellulaire
Secreted.
