GRO beta est un gène codé par le symbole CXCL2. Communément appelé aussi: C-X-C motif chemokine 2; Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha; CXCL2; GRO2; GROB; MIP2A; SCYB2. GRO beta a une masse de 11.39kDa et une longueur d'acide aminé de 107.
Nous proposons 2 GRO beta kits ELISA pour la détection qualitative ou quantitative de GRO beta à partir d'échantillons Humain.
Informations sur les Gènes et les Protéines
Résumé UniProt
Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
Résumé Entrez
This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation.
Similitudes de séquence
Belongs to the intercrine alpha (chemokine CxC) family.
Modification post-traductionnelle
The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
Localisation cellulaire
Secreted.
