Specificity
This antibody recognises mouse Peroxisome proliferator-activated receptor alpha (PPAR ALPHA), a 52.2 kDa transcription factor belonging to the nuclear hormone receptor (NR1) family.Peroxisome proliferator-activated receptors are vital in the regulation of cellular differentiation, development and metabolism. PPARA is also the target of hypolipidemic fibrates, a class of drugs used in cholesterol disorders.PPARA alpha is expressed primarily in the liver, kidney, heart and skeletal muscle and is involved in the regulation of beta-oxidation of fatty acids.