Anti-PKC iota Anticorps [PRKCI/4912] (A278352)

Anticorps monoclonal [PRKCI/4912] de souris contre PKC iota pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-PKC iota Antibody [PRKCI/4912] - BSA and Azide free
Description du produit
Mouse monoclonal [PRKCI/4912] antibody to PKC iota.
Spécificité
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms ( L, , Ã·, , , l/i, m and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC L and are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
Applications
IHC-P
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 100-300, of human PKC iota. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PRKCI/4912
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
68 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-PKC iota Antibody [PRKCI/4912] (A277764).
Synonymes
aPKC lambda/iota, aPKC-lambda/iota, Atypical protein kinase C lambda/iota, Atypical protein kinase C-lambda/iota, DXS1179E, KPCI_HUMAN, MGC26534, nPKC iota, nPKC-iota, nPKCiota, PKC lambda, PKC lambda/iota, PKCI, PKCiota, PKClambda, PRKC iota, PRKC lambda/iota, PRKC-lambda/iota, PRKCI, Protein kinase C iota, Protein kinase C iota type
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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