Anti-PGP9.5 Anticorps [UCHL1/4558] (A250277)

Name: Anti-PGP9.5 Antibody [UCHL1/4558]
Brand: Antibodies.com
SKU: A250277
Price: 525.0 USD
Availability: InStock

Cliquez pour ouvrir le point de vue élargi

$525

Anticorps monoclonal [UCHL1/4558] de souris contre PGP9.5 pour WB et IHC-P.

Qualité 100 % Garantie

Garantie de Correspondance des Prix

Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 4-6 jours ouvrables.

Nous ContacterContact

Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

Garanties

Qualité 100 % Garantie

Garantie de Correspondance des Prix

Mots clés :

Anticorps Monospécifique Neuronal Marker

Spécifications

Nom du produit

Anti-PGP9.5 Antibody [UCHL1/4558]

Description du produit

Mouse monoclonal [UCHL1/4558] antibody to PGP9.5.

Spécificité

This antibody reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinsons disease.

Applications

WB, IHC-P

Recommander des dilutions

WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Reactivité

Human, Rat

Réactivité croisée

This antibody is predicted to cross react with Horse, Bovine, Porcine, and Mouse based on sequence homology.

Immunogène

Synthetic peptide, around amino acids 185-214, of human UCHL1 protein, conjugated to KLH.

Hôte

Mouse

Clonalité

Monoclonal

Clone

UCHL1/4558

Isotype

IgG1

Chaînes légères

kappa

Conjuguer

Unconjugated

Purification

Protein A/G chromatography.

Concentration

200 µg/ml

Masse moléculaire

20-30 kDa

Forme du produit

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Stockage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes générales

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-PGP9.5 Antibody [UCHL1/4558] - BSA and Azide free (A253457).

Synonymes

Epididymis luminal protein 117, Epididymis secretory protein Li 53, HEL 117, HEL S 53, NDGOA, Neuron cytoplasmic protein 9.5, OTTHUMP00000218137, OTTHUMP00000218139, OTTHUMP00000218140, OTTHUMP00000218141, Park 5, PARK5, PGP 9.5, PGP95, Protein gene product 9.5, Ubiquitin C terminal esterase L1, Ubiquitin C terminal hydrolase, Ubiquitin C terminal hydrolase L1, Ubiquitin carboxyl terminal esterase L1, Ubiquitin carboxyl terminal hydrolase isozyme L1, Ubiquitin carboxyl-terminal hydrolase isozyme L1, Ubiquitin thioesterase L1, Ubiquitin thiolesterase, Ubiquitin thiolesterase L1, UCH-L1, UCHL1, UCHL1_HUMAN

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (4)

Cliquez pour ouvrir le point de vue élargi

Figure 1: Immunohistochemistry - Anti-PGP9.5 Antibody [UCHL1/4558] (A250277)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cerebellum using Anti-PGP9.5 Antibody [UCHL1/4558].

Cliquez pour ouvrir le point de vue élargi

Figure 2: Immunohistochemistry - Anti-PGP9.5 Antibody [UCHL1/4558] (A250277)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cerebellum using Anti-PGP9.5 Antibody [UCHL1/4558].

Cliquez pour ouvrir le point de vue élargi

Figure 3: Western Blot - Anti-PGP9.5 Antibody [UCHL1/4558] (A250277)

Western blot analysis of human brain tissue and T98G cell lysates using Anti-PGP9.5 Antibody [UCHL1/4558].

Cliquez pour ouvrir le point de vue élargi

Figure 4: Anti-PGP9.5 Antibody [UCHL1/4558] (A250277)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-PGP9.5 Antibody [UCHL1/4558]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.