This antibody recognises perforin, also known as cytolysin, a cytolytic protein found in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. The importance of perforin in maintaining immune homeostasis and immune surveillance is extremely well documented. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis
Applications
WB
Recommander des dilutions
WB: 0.5 - 4.0 µg/ml
Reactivité
Rat, Human, Mouse
Immunogène
Synthetic peptide corresponding to residues surrounding amino acid 568 of rat perforin.
Hôte
Rabbit
Clonalité
Polyclonal
Isotype
IgG
Conjuguer
Unconjugated
Concentration
500 µg/ml
Masse moléculaire
Approximately 70 kDa in Jurkat lysates
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 30% Glycerol, 0.5% BSA, and 0.01% Thiomersal.
Stockage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Notes générales
Rabbit anti perforin antibody recognizes perforin, also known as cytolysin, acytolyticprotein found in the granules ofcytotoxic T lymphocytes (CTLs)andNK cells. The importance of perforin in maintaining immune homeostasis and immune surveillance is extremely well documented. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis