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Anti-PD1 Anticorps (A323657)

SDS-PAGE - Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) - Antibodies.com SEC-HPLC - Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) - Antibodies.com ELISA - Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) - Antibodies.com Research in vivo - Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) - Antibodies.com
Anticorps Recombinant
$295
Product Datasheet

Anticorps monoclonal de Humanized contre PD1 pour ELISA, FACS, Functional Assay et In Vivo.

Qualité 100 % Garantie
Garantie de Correspond­ance des Prix

Frais de livraison
$40
Date de livraison
Livraison sous 7-10 jours ouvrables.

Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com

Nom du produit
Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free
Description du produit
Recombinant humanized monoclonal antibody to PD1.
Applications
ELISA, FACS, Functional Assay, In Vivo
Reactivité
Human, Cynomolgus Macaque
Hôte
Humanized
Clonalité
Monoclonal
Isotype
IgG4SP - Human IgG4 with S228P mutation
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A affinity chromatography.
Concentration
Reconstitution dependent.
Masse moléculaire
This antibody has a predicted MW of 143.44 kDa.
Pureté
> 95% (by SDS-PAGE and SEC-HPLC).
Forme du produit
Lyophilized
Reconstitution
Reconstitute with 100µl of sterile double-distilled water to bring antibody to 1mg/ml concentration. Gently shake to solubilize completely. Do not vortex!
Formulation
Lyophilized from 25mM Histadine, pH 6.2, with 8% Sucrose and 0.01% Tween80.
Stockage
Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.
Synonymes
CD279, CD279 antigen, hPD 1, hPD l, hPD-1, hSLE1, PD 1, PD-1, PDCD 1, PDCD1, PDCD1_HUMAN, Programmed cell death 1, Programmed cell death 1 protein, Programmed cell death protein 1, Protein PD 1, Protein PD-1, SLEB2, Systemic lupus erythematosus susceptibility 2
Anticorps secondaires appropriés
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.
SDS-PAGE - Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) - Antibodies.comCliquez pour ouvrir le point de vue élargi
Figure 1: SDS-PAGE - Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657)
SDS-PAGE analysis of Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) under reducing (R) conditions confirms that the purity of this antibody is greater than 95%.
SEC-HPLC - Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) - Antibodies.comCliquez pour ouvrir le point de vue élargi
Figure 2: Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657)
SEC-HPLC analysis of Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) confirms that the purity of this antibody is greater than 95%.
ELISA - Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) - Antibodies.comCliquez pour ouvrir le point de vue élargi
Figure 3: Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657)
Immobilized recombinant human PD1 protein (His tag) at 2 µg/ml is bound by Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657). EC50 = 0.0039 µg/ml.
Research in vivo - Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) - Antibodies.comCliquez pour ouvrir le point de vue élargi
Figure 4: Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657)
Pembrolizumab Biosimilar - Anti-PD1 Antibody - Low endotoxin, Azide free (A323657) inhibited the tumor growth of MC38 on human PD-1 mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 44.0% at 0.18 mpk at D37.

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