Anti-PDGF BB Anticorps (A283935)

$645

Anticorps polyclonal de lapin contre PDGF BB pour WB, ELISA, IHC-P et Functional Assays.

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-PDGF BB Antibody - BSA and Azide free
Description du produit
Rabbit polyclonal antibody to PDGF BB.
Spécificité
This antibody recognises human PDGF-BB (Platelet derived growth factor B chain), a disulphide-linked beta-chain homodimer and member of the PDGF family, released from platelet alpha-granules following trauma/platelet activation.Naturally occurring active forms of PDGF exist as dimers of two alpha chains (AA), two beta chains (BB), or a combination of both chains (AB), all of which signal through the high-affinity PDGF-Ralpha receptor, and the latter two of which can also signal through the PDGF-Rbeta receptor. PDGFs are potent mitogens for a variety of cells including those of the connective tissue, bone and cartilage, blood and smooth muscle cells, and are involved in several biological processes including chemotaxis, hyperplasia and embryonic neurogenesis.The expression of PDGF-BB is associated with autocrine growth stimulation and the formation of various tumour types.
Applications
WB, ELISA, IHC-P, Functional Assays
Recommander des dilutions
ELISA: 0.5 - 2 µg/ml, Functional Assays: 0.03 - 0.04 µg/ml, WB: 0.1 - 0.2 µg/ml
Reactivité
Human
Immunogène
Recombinant human PDGF-BB.
Hôte
Rabbit
Clonalité
Polyclonal
Isotype
IgG
Conjuguer

Unconjugated

Concentration
1 mg/ml after reconstitution.
Forme du produit
Lyophilized
Reconstitution
Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.
Formulation
Supplied in Phosphate Buffered Saline.
Stockage
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Notes générales
Rabbit anti Human PDGF BB Homodimer antibody recognizes human PDGF-BB (Platelet derived growth factor B chain), a disulphide-linked beta-chain homodimer and member of the PDGF family, released from platelet alpha-granules following trauma/platelet activation.Naturally occurring active forms of PDGF exist as dimers of two alpha chains (AA), two beta chains (BB), or a combination of both chains (AB), all of which signal through the high-affinity PDGF-Ralpha receptor, and the latter two of which can also signal through the PDGF-Rbeta receptor. PDGFs are potent mitogens for a variety of cells including those of the connective tissue, bone and cartilage, blood and smooth muscle cells, and are involved in several biological processes including chemotaxis, hyperplasia and embryonic neurogenesis.The expression of PDGF-BB is associated with autocrine growth stimulation and the formation of various tumour types.
Synonymes
Becaplermin, c sis, FLJ12858, Oncogene SIS , PDG B chain , PDGB, PDGF 2, PDGF B, PDGF B chain, PDGF subunit B, PDGF-2, PDGF2, Pdgfb, PDGFB/COL1A1 fusion gene , PDGFB_HUMAN, Platelet derived growth factor 2, Platelet derived growth factor B chain, Platelet derived growth factor beta polypeptide, Platelet derived growth factor beta polypeptide (oncogene SIS) , Platelet derived growth factor subunit B, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, Proto oncogene c Sis, Proto-oncogene c-Sis, Simian sarcoma viral (v sis) oncogene homolog, SIS, SSV, V sis platelet derived growth factor beta polypeptide
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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