Anti-PD-L2 Anticorps [24F.10C12] (A279148)

$375

Anticorps monoclonal [24F.10C12] de souris contre PD-L2 pour Flow Cytometry, IHC-Fr et Functional Assays.

Alternative Formats and ConjugatesAlternative Formats

PE
Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-PD-L2 Antibody [24F.10C12]
Description du produit
Mouse monoclonal [24F.10C12] antibody to PD-L2.
Spécificité
This antibody recognises human CD273, also known as B7-DC and Programmed Death Ligand 2 (PD-L2). CD273 is a ~42 kDa member of the immunoglobulin receptor superfamily, and is a ligand for CD279 (PD-1). CD273 is primarily expressed on dendritic cells, and its expression can be induced on inflammatory macrophages when activated by interleukin 4 or Th2 cells.CD273 functions to inhibit T-cell proliferation by blocking cell cycle progression and cytokine production, and is particularly important in the maintenance of self tolerance.Clone 24F.10C12 is reported to block CD273 activity and enhance T-cell proliferation (Brown et al, 2003)
Applications
Flow Cytometry, IHC-Fr, Functional Assays
Reactivité
Human
Immunogène
Human CD273.
Hôte
Mouse
Clonalité
Monoclonal
Clone
24F.10C12
Isotype
IgG2a
Conjuguer

Unconjugated

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Pureté
>95% (by SDS-PAGE).
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.
Stockage
Store undiluted at 4°C. Do not freeze!
Notes générales
Mouse anti Human CD273 antibody, clone 24F.10C12 detects human CD273, also known as B7-DC and Programmed Death Ligand 2 (PD-L2). CD273 is a ~42 kDa member of the immunoglobulin receptor superfamily, and is a ligand for CD279 (PD-1). CD273 is primarily expressed on dendritic cells, and its expression can be induced on inflammatory macrophages when activated by interleukin 4 or Th2 cells.CD273 functions to inhibit T-cell proliferation by blocking cell cycle progression and cytokine production, and is particularly important in the maintenance of self tolerance.Clone 24F.10C12 is reported to block CD273 activity and enhance T-cell proliferation (Brown et al, 2003)
Synonymes
B7 dendritic cell molecule, B7-DC, B7DC, bA574F11.2, Btdc, Butyrophilin B7 DC, Butyrophilin B7-DC, Butyrophilin B7DC, CD 273, CD273, CD273 antigen, MGC142238, MGC142240, PD 1 ligand 2, PD L2, PD-1 ligand 2, PD1 ligand 2, PD1L2_HUMAN, PDCD 1 ligand 2, PDCD1 ligand 2, PDCD1L2, Pdcd1lg2, PDL 2, PDL2, Programmed cell death 1 ligand 2, Programmed death ligand 2
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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