Anti-PAX3 Anticorps [PAX3/8426] (A315467)

$765

Anticorps monoclonal [PAX3/8426] de souris contre PAX3 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-PAX3 Antibody [PAX3/8426]
Description du produit
Mouse monoclonal [PAX3/8426] antibody to PAX3.
Spécificité
Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.
Applications
IHC-P
Contrôle positif
Human skin and skeletal muscle tissue.
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 150-350) of human PAX3 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PAX3/8426
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
56 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
CDHS, HUP 2, HUP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, Paired box 3, Paired box gene 3, Paired box homeotic gene 3, Paired box protein Pax 3, Paired box protein Pax-3, Paired box protein Pax3, Paired domain gene 3, Paired domain gene HuP2, PAX 3, PAX3/FKHR fusion gene, PAX3_HUMAN, Sp, splotch, Waardenburg syndrome 1, WS 1, WS1, WS3
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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