Notes générales
Mouse anti Parainfluenza virus 1 antibody, clone 251/12A recognises an epitope within the fusion protein of parainfluenza virus 1 (HPIV-1), an enveloped single-stranded RNA virus of the Paramyxoviridae family.Parainfluenza viruses are genetically and antigenically divided into the four types HPIV1-4, with HPIV-1, -2 and -3 being major causative agents of lower respiratory infections in the young and immunologically vulnerable. The fusion protein of all HPIV, is a ~60-66 kDa surface glycoprotein, integral in the fusion of virus host-cell membranes, and the subsequent infection of a host cell by the viral nucleocapsid.