Anti-pan Cytokeratin Anticorps [PCK/3150] (A254144)

Anti-pan Cytokeratin Antibody [PCK/3150] - BSA and Azide free

Mouse monoclonal [PCK/3150] antibody to pan Cytokeratin.

This antibody demonstrates a broad spectrum of cytokeratin reactivity. In normal tissues, this antibody is reactive with most epithelial types, including: bile ducts and hepatocytes in liver, bladder epithelium, breast ducts, bronchial epithelium, endometrium, intestinal epithelium of stomach, duodenum, ileum, colon, rectum, pancreas, ovarian epithelium, pancreatic acini, pituitary acini, pneumocytes, prostate, thyroid, skin (positive on the basal layer and negative on the superficial layers of squamous epithelium), and apocrine and sweat glands. In tumors, this antibody is reactive with most carcinomas, including breast, transitional cell (TCC), renal cell (RCC), lung adenocarcinoma, lung small cell, lung squamous cell, endometrial, prostate, ovarian, hepatocellular (HCC), colorectal CA, stomach and thyroid. This antibody is negative in certain normal tissues, including: brain, lymphocytes, all cells of hematolymphoid origin, muscle, brain, nerves, endothelium, and in certain tumors including: most melanomas, sarcomas, lymphomas, primitive neuroectodermal tumors (PNET) / Ewings, and gastrointestinal stromal tumors (GIST). Positivity has been seen on some dendritic cells in lymph nodes, some endothelia, and some muscle cells.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human, Canine, Feline

Crude cytokeratin extract prepared from RT-4 and MCF-7 cells.

Mouse

Monoclonal

PCK/3150

kappa

Unconjugated

Protein A/G chromatography.

1 mg/ml

40-67 kDa (Multiple)

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-pan Cytokeratin Antibody [PCK/3150] (A250964).