Anti-p63 Antibody (A283233)

Anti-p63 Antibody

Rabbit polyclonal antibody to p63.

This antibody recognises an epitope within the C-terminal (CT) region of tumour protein p63, otherwise known as tumour protein p73-like (p73L), a widely expressed nuclear protein and homologue of tumour suppressor p53, which acts as a sequence-specific DNA binding transcriptional activator/repressor. p63, vital for the development of the prostate and selectively expressed by normal prostate basal cells, has been shown to be a promising complementary basal cell specific marker to High Molecular Weight-Cytokeratin (HMW-CK), for the differential diagnosis of benign prostatic lesions and prostatic carcinoma. Rabbit anti p63 antibody is reported as suitable for use in immunocytochemistry.

WB, ELISA

ELISA: 1:100,000, WB: 1:1,000

Human, Mouse

Synthetic peptide sequence C-NFDMDARRNKQQRIKEEGE corresponding to amino acids 662-680 within the C-terminus of p63.

C-NFDMDARRNKQQRIKEEGE

Rabbit

Polyclonal

IgG

Approximately 75 kDa in mouse lung and human tumour cell line K562 (protein degredation is as expected).

Liquid

Supplied in Phosphate Buffered Saline with 0.1% BSA and 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti p63 antibody recognizes an epitope within the C-terminal (CT) region of tumour protein p63, otherwise known as tumour protein p73-like (p73L), a widely expressed nuclear protein and homologue of tumour suppressor p53, which acts as a sequence-specific DNA binding transcriptional activator/repressor. p63, vital for the development of the prostate and selectively expressed by normal prostate basal cells, has been shown to be a promising complementary basal cell specific marker to High Molecular Weight-Cytokeratin (HMW-CK), for the differential diagnosis of benign prostatic lesions and prostatic carcinoma. Rabbit anti p63 antibody is reported as suitable for use in immunocytochemistry.

Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, KET, p40, p51, P73H, P73L, TP63, TP73L, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like