Recombinant Anti-p21 Anticorps [CIP1/4377R] (A248091)

Anticorps monoclonal [CIP1/4377R] de lapin contre p21 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-p21 Antibody [CIP1/4377R]
Description du produit
Recombinant rabbit monoclonal [CIP1/4377R] antibody to p21.
Spécificité
This antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Applications
IHC-P
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Synthetic peptide corresponding to amino acids 1-100 of p21 protein.
Hôte
Rabbit
Clonalité
Monoclonal
Clone
CIP1/4377R
Isotype
IgG
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
21 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-p21 Antibody [CIP1/4377R] - BSA and Azide free (A251274).
Synonymes
CAP20, CDK-interacting protein 1, CDKI, CDKN1, Cdkn1a, CDN1A_HUMAN, CIP1, Cyclin Dependent Kinase Inhibitor 1A, Cyclin-dependent kinase inhibitor 1, Cyclin-dependent kinase inhibitor 1A (P21), Cyclin-dependent kinase inhibitor 1A (p21, Cip1), DNA Synthesis Inhibitor, MDA-6, MDA6, Melanoma differentiation-associated protein, Melanoma differentiation-associated protein 6, P21 protein, p21CIP1, p21Cip1/Waf1, p21WAF, PIC1, SDI1, SLC12A9, WAF1, Wild type p53 activated fragment 1, Wild type p53 activated fragment 1 (WAF1), Wildtype p53-activated fragment 1
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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