Anti-NME2 Anticorps [NME2/6434] (A316782)

$765

Anticorps monoclonal [NME2/6434] de souris contre NME2 pour WB et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-NME2 Antibody [NME2/6434] - BSA and Azide free
Description du produit
Mouse monoclonal [NME2/6434] antibody to NME2.
Spécificité
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
Applications
WB, IHC-P
Contrôle positif
PC3, A549, HeLa or Jurkat cells. Ubiquitously expressed in all tissues.
Recommander des dilutions
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human NME2 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
NME2/6434
Isotype
IgG2
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
17 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
C myc purine binding transcription factor PUF, C myc transcription factor, C-myc purine-binding transcription factor PUF, epididymis secretory sperm binding protein Li 155an, HEL-S-155an, Histidine protein kinase NDKB, MGC111212, MGC2212, NDK B, NDKB, NDKB_HUMAN, NDP kinase B, NDPK B, NDPKB, NM23 H2, nm23-H2, NM23B, NME/NM23 nucleoside diphosphate kinase 2, Non metastatic cells 2, protein (NM23B) expressed in, non-metastatic cells 2, protein (NM23) expressed in, Nucleoside diphosphate kinase B, Nucleotide diphosphate kinase B, PUF
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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