Anti-NeuroD2 Antibody [PCRP-NEUROD2-1G1] (A277723)

Mouse monoclonal [PCRP-NEUROD2-1G1] antibody to NeuroD2 for ELISA, IP, Flow Cytometry and IF.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-NeuroD2 Antibody [PCRP-NEUROD2-1G1]
Description
Mouse monoclonal [PCRP-NEUROD2-1G1] antibody to NeuroD2.
Specificity
Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (β2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
Applications
ELISA, IP, Flow Cytometry, IF
Dilutions
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human NeuroD2 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-NEUROD2-1G1
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
41 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-NeuroD2 Antibody [PCRP-NEUROD2-1G1] - BSA and Azide free (A278311).
Synonyms
BHLHA1, Class A basic helix-loop-helix protein 1, NDRF, NeuroD-related factor, Neurogenic differentiation factor 2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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