Recombinant Anti-N Cadherin Anticorps [CDH2/8998R] (A315362)

$765

Anticorps monoclonal [CDH2/8998R] de lapin contre N Cadherin pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-N Cadherin Antibody [CDH2/8998R]
Description du produit
Recombinant rabbit monoclonal [CDH2/8998R] antibody to N Cadherin.
Spécificité
Recognizes a protein of ~140kDa, identified as N-Cadherin (NCAD), also known as CD325. NCAD is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells.Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.
Applications
IHC-P
Contrôle positif
Human heart, pancreas or cerebral cortex (IHC).
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 605-905) of human CDH2 protein. The exact sequence is proprietary.
Hôte
Rabbit
Clonalité
Monoclonal
Clone
CDH2/8998R
Isotype
IgG
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
130-140 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
CADH2_HUMAN, Cadherin 2, Cadherin 2 N cadherin neuronal, Cadherin 2 type 1, Cadherin 2 type 1 N cadherin neuronal, Cadherin 2, type 1, N-cadherin (neuronal), Cadherin-2, Cadherin2, Calcium dependent adhesion protein neuronal, CD325, CD325 antigen, CDH2, CDHN, CDw325, CDw325 antigen, N cadherin 1, N-cadherin, NCAD, Neural cadherin, OTTHUMP00000066304, OTTHUMP00000067378
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Produits alternatifs à Anti-N Cadherin Anticorps [CDH2/8998R] (A315362)

Haut