Spécificité
This antibody recognises human myoglobin, a single-chain globular ~17kDa protein containing a heme prosthetic group localized to skeletal muscle. Myoglobin is responsible for the storage and movement of oxygen in muscle tissue. Myoglobin is released from injured muscle into the bloodstream, making it a sensitive marker for all muscle injury. It is commonly used in combination with troponin as a marker for myocardial damage in heart attacks. It is filtered by the kidneys, but is a potential cause of renal failure as it is toxic to the renal tubular epithelium.