Recombinant Anti-MUC2 Anticorps [rMLP/842] (A249422)

Anti-MUC2 Antibody [rMLP/842]

Recombinant mouse monoclonal [rMLP/842] antibody to MUC2.

This antibody recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

A synthetic peptide of 29 amino acids from MUC2 protein, coupled to KLH.

KYPTTTPISTTTMVTPTPTPTGTQTPTTT

Mouse

Monoclonal

rMLP/842

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

520 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MUC2 Antibody [rMLP/842] - BSA and Azide free (A252602).

Intestinal mucin 2, Intestinal mucin-2, MLP, MUC 2, MUC-2, MUC2_HUMAN, Mucin 2, Mucin 2 intestinal, Mucin 2 intestinal/tracheal, Mucin 2 oligomeric mucus/gel forming, Mucin 2 precursor, Mucin 2 tracheal, Mucin like protein, Mucin-2, Mucin2, SMUC