Anti-MUC1 Anticorps [HMPV] (A249395)

Anticorps monoclonal [HMPV] de souris contre MUC1 pour WB, Flow Cytometry, IF et IHC.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-MUC1 Antibody [HMPV]
Description du produit
Mouse monoclonal [HMPV] antibody to MUC1.
Spécificité
This antibody recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein.The dominant epitope of This antibody is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (200kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This antibody reacts with both normal and malignant epithelia of various tissues including breast and colon.
Applications
WB, Flow Cytometry, IF, IHC
Recommander des dilutions
WB: 1-2 µg/ml, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 0.5-1 µg/ml
Reactivité
Human
Immunogène
Human breast cancer cell line ZR-75 cells.
Hôte
Mouse
Clonalité
Monoclonal
Clone
HMPV
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein G chromatography.
Concentration
200 µg/ml
Masse moléculaire
265-400 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MUC1 Antibody [HMPV] - BSA and Azide free (A252575).
Synonymes
ADMCKD, ADMCKD1, Breast carcinoma associated antigen DF3, Breast carcinoma-associated antigen DF3, CA 15-3, CA15 3, CA15 3 antigen, CA15.3, Cancer antigen 15-3, Carcinoma associated mucin, Carcinoma-associated mucin, CD 227, CD227, DF3 antigen, EMA, Episialin, H23 antigen, H23AG, KL 6, KL-6, KL6, Krebs von den Lungen-6, MAM 6, MAM6, MCD, MCKD, MCKD1, Medullary cystic kidney disease 1 (autosomal dominant), Medullary cystic kidney disease, autosomal dominant, MUC 1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, MUC1_HUMAN, Mucin 1, Mucin 1 transmembrane, Mucin 1, cell surface associated, Mucin-1 subunit beta, Peanut reactive urinary mucin, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor associated epithelial membrane antigen, Tumor associated epithelial mucin, Tumor associated mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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