Anti-MUC1 Anticorps [C595 (NCRC48)] (PE) (A320248)

Ce produit est discontinué

Anti-MUC1 Anticorps [C595 (NCRC48)] (PE) (A320248) a été abandonné et n'est plus disponible.

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Nom du produit
Anti-MUC1 Antibody [C595 (NCRC48)] (PE)
Description du produit
Mouse monoclonal [C595 (NCRC48)] antibody to MUC1 (PE).
Spécificité
This antibody recognises CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases.recognises the peptide epitope ARG-PRO-ALA-PRO within the protein core of the mucin.
Applications
Flow Cytometry
Recommander des dilutions
Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reactivité
Human
Immunogène
Urinary MUC-1 mucin.
Hôte
Mouse
Clonalité
Monoclonal
Clone
C595 (NCRC48)
Isotype
IgG3
Conjuguer

PE

Excitation: 565nm, Emission: 578nm

Purification
Protein A affinity chromatography.
Concentration
Reconstitution dependent.
Forme du produit
Lyophilized
Reconstitution
Reconstitute with 1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution.
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.
Stockage
Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Notes générales
Mouse anti Human CD227 antibody, clone C595 (NCRC48) recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases.Mouse anti Human CD227 antibody, clone C595 recognizes the peptide epitope ARG-PRO-ALA-PRO within the protein core of the mucin.
Synonymes
ADMCKD, ADMCKD1, Breast carcinoma associated antigen DF3, Breast carcinoma-associated antigen DF3, CA 15-3, CA15 3, CA15 3 antigen, CA15.3, Cancer antigen 15-3, Carcinoma associated mucin, Carcinoma-associated mucin, CD 227, CD227, DF3 antigen, EMA, Episialin, H23 antigen, H23AG, KL 6, KL-6, KL6, Krebs von den Lungen-6, MAM 6, MAM6, MCD, MCKD, MCKD1, Medullary cystic kidney disease 1 (autosomal dominant), Medullary cystic kidney disease, autosomal dominant, MUC 1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, MUC1_HUMAN, Mucin 1, Mucin 1 transmembrane, Mucin 1, cell surface associated, Mucin-1 subunit beta, Peanut reactive urinary mucin, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor associated epithelial membrane antigen, Tumor associated epithelial mucin, Tumor associated mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.
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