Anti-MR1 Anticorps [MR1/7579] (A316714)

$765

Anticorps monoclonal [MR1/7579] de souris contre MR1 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-MR1 Antibody [MR1/7579] - BSA and Azide free
Description du produit
Mouse monoclonal [MR1/7579] antibody to MR1.
Spécificité
MR1 (major histocompatibility complex, class I-related), also known as HLALS, is a 341 amino acid single-pass membrane protein that localizes to the endoplasmic reticulum, as well as to the extracellular side of the cell membrane, and contains one Ig-like C1-type domain. Expressed ubiquitously, MR1 exists as a heterodimer with b-2-Microglobulin and plays an important role in antigen presentation, specifically in the development and expansion of mucosalassociated invariant T cells (MAITs). MAITs are located in the gut and are involved in monitoring flora levels, as well as in conveying distress signals to other areas of the body, indicating a role for MR1 in proper digestion and immune system function. MR1 exists as four alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 1.
Applications
IHC-P
Contrôle positif
Human kidney, placenta or tonsil.
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 50-250) of human MR1 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
MR1/7579
Isotype
IgG2
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
39 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
Class I histocompatibility antigen like protein, Class I histocompatibility antigen-like protein, HLALS, HMR1_HUMAN, Major histocompatibility complex class I like sequence, Major histocompatibility complex class I related, Major histocompatibility complex class I related gene protein, Major histocompatibility complex class I related isoform CRA a, Major histocompatibility complex class I related isoform CRA c, Major histocompatibility complex class I related isoform CRA d, Major histocompatibility complex class I-related gene protein, MHC class I like antigen MR 1, MHC class I like antigen MR1, MHC class I related gene protein, MHC class I related protein 1 isoform B, MHC class I related protein 1 isoform C, MHC class I-related gene protein, MR 1, Mr1 protein, MR1B, MR1C
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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