Anti-MMP3 Anticorps [MMP3/2806] (A249371)

Anticorps monoclonal [MMP3/2806] de souris contre MMP3 pour ELISA et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-MMP3 Antibody [MMP3/2806]
Description du produit
Mouse monoclonal [MMP3/2806] antibody to MMP3.
Spécificité
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
Applications
ELISA, IHC-P
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 236-363, of human MMP3 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
MMP3/2806
Isotype
IgG2c
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A chromatography.
Concentration
200 µg/ml
Masse moléculaire
57 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MMP3 Antibody [MMP3/2806] - BSA and Azide free (A252551).
Synonymes
CHDS6, Matrix metalloproteinase 3, Matrix metalloproteinase-3, MGC126102, MGC126103, MGC126104, MMP 3, MMP-3, MMP3_HUMAN, Proteoglycanase , SL-1, SL1 , STMY, STMY1, STR1, Stromelysin 1, Stromelysin-1, Transin 1, Transin-1
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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