Anti-MEF2B Anticorps [PCRP-MEF2B-2F9] (A277524)

Name: Anti-MEF2B Antibody [PCRP-MEF2B-2F9]
Brand: Antibodies.com
SKU: A277524
Price: 525.0 USD
Availability: InStock

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$525

Anticorps monoclonal [PCRP-MEF2B-2F9] de souris contre MEF2B pour IP, WB, Flow Cytometry et IF.

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Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 4-6 jours ouvrables.

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Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

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Mots clés :

Anticorps Monospécifique

Spécifications

Nom du produit

Anti-MEF2B Antibody [PCRP-MEF2B-2F9]

Description du produit

Mouse monoclonal [PCRP-MEF2B-2F9] antibody to MEF2B.

Spécificité

The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

Applications

IP, WB, Flow Cytometry, IF

Recommander des dilutions

IP: 1-2µg / 100-500µg proteins, WB: 1-2 µg/ml, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Reactivité

Human

Immunogène

Recombinant full-length human MEF2B protein.

Hôte

Mouse

Clonalité

Monoclonal

Clone

PCRP-MEF2B-2F9

Isotype

IgG2a

Conjuguer

Unconjugated

Purification

Protein A/G chromatography.

Concentration

200 µg/ml

Masse moléculaire

160 kDa

Forme du produit

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Stockage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes générales

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MEF2B Antibody [PCRP-MEF2B-2F9] - BSA and Azide free (A278112).

Synonymes

MADS box transcription enhancer factor 2, MDS1 EVI1, MEF2B_HUMAN, Myocyte enhancer factor 2B, Myocyte specific enhancer factor 2B, Myocyte-specific enhancer factor 2B, PRDM3, RSRFR2, Serum response factor like protein 2, Serum response factor-like protein 2, XMEF2

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (3)

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Figure 1: Flow Cytometry - Anti-MEF2B Antibody [PCRP-MEF2B-2F9] (A277524)

Flow cytometric analysis of PFA-fixed HeLa cells using Anti-MEF2B Antibody [PCRP-MEF2B-2F9] followed by Goat Anti-Mouse IgG (CF® 488) (Blue). Unstained cells (Red).

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Figure 2: Immunofluorescence - Anti-MEF2B Antibody [PCRP-MEF2B-2F9] (A277524)

Immunofluorescent analysis of PFA-fixed HeLa cells stained with Anti-MEF2B Antibody [PCRP-MEF2B-2F9] followed by Goat Anti-Mouse IgG (CF® 488) (Green). CF® 640A Phalloidin (Red).

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Figure 3: Anti-MEF2B Antibody [PCRP-MEF2B-2F9] (A277524)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-MEF2B Antibody [PCRP-MEF2B-2F9]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.