Anti-MCM6 Anticorps [MCM6/3000] (A252479)

Anticorps monoclonal [MCM6/3000] de souris contre MCM6 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-MCM6 Antibody [MCM6/3000] - BSA and Azide free
Description du produit
Mouse monoclonal [MCM6/3000] antibody to MCM6.
Spécificité
The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro.
Applications
IHC-P
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 228-368, of human MCM6 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
MCM6/3000
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
105 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-MCM6 Antibody [MCM6/3000] (A249299).
Synonymes
DNA replication licensing factor MCM6, MCG40308, MCM6 minichromosome maintenance deficient 6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6_HUMAN, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6, Mis5, MIS5 homolog, p105MCM
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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