Anti-Macrophage Inflammatory Protein 3 alpha Antibody - BSA and Azide free (A283932)

Anti-Macrophage Inflammatory Protein 3 alpha Antibody - BSA and Azide free

Rabbit polyclonal antibody to Macrophage Inflammatory Protein 3 alpha.

This antibody recognises human MIP-3 alpha, (Macrophage Inflammatory Protein 3 alpha), otherwise known as CCL20, a 70 amino acid CC chemokine predominantly expressed by the liver, lymph nodes, appendix, spleen and pancreas and also by the thymus, small intestine, foetal lungs and PBLs.MIP-3 alpha acts as a chemoattractant for memory T lymphocytes, immature dendritic cells and B lymphocytes, being the only CC chemokine known to bind to the G-protein linked 7-transmembrane receptor CCR6. Further properties of MIP-3 alpha include antimicrobial activity, inhibition of the in vitro proliferation of bone marrow immature myeloid progenitors and the stimulation of the growth and migration of pancreatic carcinoma cells.

WB, ELISA, IHC-P, Functional Assays

ELISA: 0.5 µg/ml, Functional Assays: 15.0 - 18.0 µg/ml, WB: 0.1 - 0.2 µg/ml

Human

Recombinant human MIP-3 alpha.

Rabbit

Polyclonal

IgG

Lyophilized

Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human MIP-3 alpha antibody recognizes human MIP-3 alpha, (Macrophage Inflammatory Protein 3 alpha), otherwise known as CCL20, a 70 amino acid CC chemokine predominantly expressed by the liver, lymph nodes, appendix, spleen and pancreas and also by the thymus, small intestine, foetal lungs and PBLs.MIP-3 alpha acts as a chemoattractant for memory T lymphocytes, immature dendritic cells and B lymphocytes, being the only CC chemokine known to bind to the G-protein linked 7-transmembrane receptor CCR6. Further properties of MIP-3 alpha include antimicrobial activity, inhibition of the in vitro proliferation of bone marrow immature myeloid progenitors and the stimulation of the growth and migration of pancreatic carcinoma cells.