Anti-Langerin Anticorps [LGRN/7428] (A315240)

$765

Anticorps monoclonal [LGRN/7428] de souris contre Langerin pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Langerin Antibody [LGRN/7428]
Description du produit
Mouse monoclonal [LGRN/7428] antibody to Langerin.
Spécificité
Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
Applications
IHC-P
Contrôle positif
Human skin.
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 50-250) of human Langerin protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
LGRN/7428
Isotype
IgG
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
48 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
C type lectin domain family 4 member K, C-type lectin domain family 4 member K, CD 207, CD207, CD207 antigen, CD207 antigen, langerin, CD207 molecule, CLC4K_HUMAN, CLEC 4K, CLEC4K, Langerhans cell specific c type lectin, RGD1565913
Contrôles isotype
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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