Anti-Lambda Light Chain Anticorps [LcN-2] (CF® 488) (A251197)

Ce produit est discontinué

Anti-Lambda Light Chain Anticorps [LcN-2] (CF® 488) (A251197) a été abandonné et n'est plus disponible.

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Nom du produit
Anti-Lambda Light Chain Antibody [LcN-2] (CF® 488)
Description du produit
Mouse monoclonal [LcN-2] antibody to Lambda Light Chain (CF® 488).
Spécificité
This antibody is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Applications
Flow Cytometry, IF
Recommander des dilutions
Flow Cytometry: 5 µl / million cells or 5 µl / 100 µl whole blood, IF: 1:50-1:100
Reactivité
Human
Immunogène
Purified human IgG protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
LcN-2
Isotype
IgG2a
Chaînes légères
kappa
Conjuguer

CF® 488

Excitation: 490nm, Emission: 515nm

Purification
Protein A/G chromatography.
Concentration
100 µg/ml
Masse moléculaire
~22.5 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Store at 4-8°C. Antibody is stable for 24 months.
Synonymes
Bence Jones protein, BJP, Constant region of lambda light chains, Ig lambda chain C regions, ig lambda-6 chain C region, IGLC, IGLC 1, IGLC 2, IGLC 3, IGLC1, IGLC2, IGLC3, IGLC6, IGLV, Immunoglobulin lambda constant 1, Immunoglobulin lambda constant regin 1, immunoglobulin lambda gene cluster, Immunoglobulin lambda locus, Immunoglobulin lambda variable cluster, Immunoglobulin: lambda light chain, Mcg marker, Paraprotein
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.
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