This antibody recognises CD339, otherwise known as Jagged1, one of the five major ligands of the Notch signaling pathway, which is activated through the binding of specific ligands to the Notch receptors Notch 1-4.In humans, mutations in the JAG1 gene are responsible for the autosomal dominant multisystem disorder Alagille syndrome 1 (ALGS1)
Applications
Flow Cytometry, IHC-Fr
Recommander des dilutions
Use 10µl of the suggested working dilution to label 1x106 cells in 100µl.
Reactivité
Mouse, Rat
Immunogène
CHO cells expressing Jagged1.
Hôte
Hamster
Clonalité
Monoclonal
Clone
HMJ1-29
Isotype
IgG
Conjuguer
Unconjugated
Purification
Protein G affinity chromatography.
Concentration
1 mg/ml
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Stockage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Notes générales
Hamster anti Mouse CD339 antibody, clone HMJ1-29 specifically recognizes CD339, otherwise known as Jagged1, one of the five major ligands of the Notch signaling pathway, which is activated through the binding of specific ligands to the Notch receptors Notch 1-4.In humans, mutations in the JAG1 gene are responsible for the autosomal dominant multisystem disorder Alagille syndrome 1 (ALGS1)
Synonymes
AGS, AHD, AWS, CD 339, CD339, CD339 antigen, Headturner, hJ1, Htu, Jag 1, Jag1, JAG1_HUMAN, Jagged 1, Jagged1 (Alagille syndrome), JAGL1, MGC104644, OTTHUMP00000030278, Protein jagged-1, Ser 1, Ser1, Serrate 1, Slalom
