This antibody recognises human interferon beta (IFN Beta), a ~22 kDa cytokine with wide-ranging antiviral, antimicrobial and antitumor effects. Interferons also serve to activate macrophages, natural killer cells and the presentation of antigens to the immune system by the major histocompatibility complex. The production of interferon is induced in response to microbes and other cytokines. The interferons are widely used to treat a variety of diseases and IFNB in particular is used to treat relapsing-remitting multiple sclerosis. recognises glycosylated and non-glycosylated human IFNß and there is no cross-reactivity with human interferon alpha or human interferon gamma.

Applications

WB, ELISA

Reactivité

Human

Immunogène

Recombinant full length human IFN Beta, expressed in E.coli.

Hôte

Mouse

Clonalité

Monoclonal

Clone

BB4

Isotype

IgG2a

Conjuguer

Unconjugated

Purification

Protein G affinity chromatography of tissue culture supernatant.

Concentration

1 mg/ml

Forme du produit

Liquid

Formulation

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Stockage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Notes générales

Mouse anti Human IFN beta antibody, clone BB4 recognizes human interferon beta (IFN Beta), a ~22 kDa cytokine with wide-ranging antiviral, antimicrobial and antitumor effects. Interferons also serve to activate macrophages, natural killer cells and the presentation of antigens to the immune system by the major histocompatibility complex. The production of interferon is induced in response to microbes and other cytokines. The interferons are widely used to treat a variety of diseases and IFNB in particular is used to treat relapsing-remitting multiple sclerosis. Mouse anti Human IFN beta antibody, clone BB4 recognizes glycosylated and non-glycosylated human IFNß and there is no cross-reactivity with human interferon alpha or human interferon gamma.

Synonymes

beta-interferon, Fibroblast interferon, IFB, IFF, IFN beta, IFN-beta, IFNB, IFNB 1, IFNB1, IFNB_HUMAN, Interferon beta 1 fibroblast, Interferon beta precursor, MGC96956

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.