This antibody recognises interleukin-9 (IL-9), also known as cytokine P40 and T cell growth factor P40. IL-9 is a member of the common gamma chain receptor cytokine family that is expressed by multiple cell types including T cell subsets, neutrophils, eosinophils, natural killer T cells and mast cells (Noelle & Nowak 2010, Chakraborty et al. 2019).IL-9 is a ligand of IL-9 receptor alpha (IL-9RA) and upon binding of IL-9 to its receptor the JAK, PI3K, STAT and MAPK signaling pathways can be activated. This can then result in the stimulation of expression of genes that play roles in transplant tolerance, allergies, autoimmunity and parasitic infection.

Applications

WB, ELISA

Recommander des dilutions

ELISA: 0.5 µg/ml - 2.0 µg/ml, WB: 0.1 µg/ml - 0.2 µg/ml

Reactivité

Mouse

Immunogène

E. coli derived recombinant mouse interleukin-9.

Hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Conjuguer

Unconjugated

Concentration

1 mg/ml after reconstitution.

Forme du produit

Lyophilized

Reconstitution

Reconstitute with 0.1 ml of distilled water.

Formulation

Supplied in Phosphate Buffered Saline.

Stockage

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Notes générales

Rabbit anti Mouse interleukin-9 antibody, recognizes interleukin-9 (IL-9), also known as cytokine P40 and T cell growth factor P40. IL-9 is a member of the common gamma chain receptor cytokine family that is expressed by multiple cell types including T cell subsets, neutrophils, eosinophils, natural killer T cells and mast cells (Noelle & Nowak 2010, Chakraborty et al. 2019). IL-9 is a ligand of IL-9 receptor alpha (IL-9RA) and upon binding of IL-9 to its receptor the JAK, PI3K, STAT and MAPK signaling pathways can be activated (Chakraborty et al. 2019). This can then result in the stimulation of expression of genes that play roles in transplant tolerance, allergies, autoimmunity and parasitic infection (Noelle & Nowak 2010).

Synonymes

Cytokine P40, Homolog of mouse T cell and mast cell growth factor 40 , HP40, IL 9, IL9, IL9_HUMAN, Interleukin 9 , Interleukin-9, Mast cell growth factor , MCGF, Megakaryoblast growth factor, P40, p40 cytokine , p40 T cell and mast cell growth factor, T cell growth factor 3, T cell growth factor p40 , T-cell growth factor P40, TCGF 3

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.