Anti-IL-15 Anticorps (A283818)

Anti-IL-15 Antibody - BSA and Azide free

Rabbit polyclonal antibody to IL-15.

This antibody recognises human IL-15 (Interleukin-15), a 14kDa immunomodulatory glycoprotein expressed by multiple tissues and cell types, which primarily stimulates T lymphocytes, but is also critical for the development and activation of natural killer cells (NK).IL-15 shares functional properties with IL-2 and binds with high affinity to the IL-15 receptor (IL-15R), consisting of the IL-15R alpha chain, and also the IL-2Rbeta and common gamma chains used by the IL-2 receptor. Affects of IL-15 have been linked with cells and tissues unrelated to the immune system, and increased expression of IL-15 has been demonstrated in Rheumatoid Arthritis (RA), ulcerative colitis (UC) Chron’s disease (CD) and lymphoid malignancies, and also conditions affiliated with HIV and HTLV-1 infection.Rabbit anti Human Interleukin-15 antibody will neutralise IL-15 activity in bioassay systems.

IP, WB, ELISA, IHC-P, Functional Assays

ELISA: 0.5 µg/ml, Functional Assays: 0.15 - 0.2 µg/ml, WB: 0.1 - 0.2 µg/ml, For functional studies do not use Azide.

Human

Recombinant human IL-15.

Rabbit

Polyclonal

IgG

Unconjugated

Lyophilized

Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human Interleukin-15 antibody recognizes human IL-15 (Interleukin-15), a 14kDa immunomodulatory glycoprotein expressed by multiple tissues and cell types, which primarily stimulates T lymphocytes, but is also critical for the development and activation of natural killer cells (NK).IL-15 shares functional properties with IL-2 and binds with high affinity to the IL-15 receptor (IL-15R), consisting of the IL-15R alpha chain, and also the IL-2Rbeta and common gamma chains used by the IL-2 receptor. Affects of IL-15 have been linked with cells and tissues unrelated to the immune system, and increased expression of IL-15 has been demonstrated in Rheumatoid Arthritis (RA), ulcerative colitis (UC) Chron’s disease (CD) and lymphoid malignancies, and also conditions affiliated with HIV and HTLV-1 infection.Rabbit anti Human Interleukin-15 antibody will neutralise IL-15 activity in bioassay systems.

IL 15, IL15, IL15_HUMAN, Interleukin 15, Interleukin-15, Interleukin15, MGC9721