Anti-ICOS Ligand Anticorps [ICOSL/3111] (A248576)

Anticorps monoclonal [ICOSL/3111] de souris contre ICOS Ligand pour ELISA, Flow Cytometry, IF et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-ICOS Ligand Antibody [ICOSL/3111]
Description du produit
Mouse monoclonal [ICOSL/3111] antibody to ICOS Ligand.
Spécificité
This antibody recognizes a protein of 36kDa, identified as ICOS-L. It is a ligand for the ICOS receptor that initiates T and B cell proliferation and cytokine secretion. ICOS-L interactions play an essential role in T cell-dependent B cell activation in peripheral lymphoid organs such as spleen and lymph nodes. ICOS-L protein is present in myeloid leukocytes, and by Northern blot there are 2.4, 3.0, and 7.0 kb transcripts in brain, heart, kidney, and liver, with lower expression in colon and thymus, and a 1.1 kb transcript in leukocytes. Tumor necrosis factor alpha (TNF), granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4) enhance its expression. LPS-induced up-regulation of ICOS-L is dependent on the MyD88-dependent signaling pathway.
Applications
ELISA, Flow Cytometry, IF, IHC-P
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 23-149, of human ICOSLG protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
ICOSL/3111
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
36 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-ICOS Ligand Antibody [ICOSL/3111] - BSA and Azide free (A251758).
Synonymes
B7 H2, B7 homolog 2, B7 homologue 2, B7 like protein Gl50, B7 related protein 1, B7-H2, B7-like protein Gl50, B7-related protein 1, B7H2, B7RP 1, B7RP-1, B7RP1, CD 275, CD275, CD275 antigen, GL 50, GL50, ICOS L, ICOS LG, ICOSL, Icoslg, ICOSL_HUMAN, Inducible T cell co stimulator ligand, KIAA0653, LICOS, Transmembrane protein B7 H2 ICOS ligand
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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