This antibody reacts with CD50 (ICAM-3), a 120-130 kDa type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes. The MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1).
Applications
Flow Cytometry, IHC-P, Functional Studies
Recommander des dilutions
FUNC: This antibody blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1), Flow Cytometry: 1-4 µg/ml, IHC-P: 10 µg/ml; Positive Control: tonsil.
Reactivité
Human
Immunogène
Leukocytes from a patient suffering from a LGL Type leukemia.
Hôte
Mouse
Clonalité
Monoclonal
Clone
MEM-04
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer
Unconjugated
Purification
Protein A chromatography.
Concentration
1 mg/ml
MW prédit
120-130 kDa
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline, pH 7.4, without Sodium Azide (0.2 µm filter sterilized). Endotoxin level is less than 0.01 EU/µg of the protein.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.