Anti-ICAM3 Anticorps [101-1D2] (A252089)

Anticorps monoclonal [101-1D2] de souris contre ICAM3 pour Flow Cytometry, IF et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-ICAM3 Antibody [101-1D2] - BSA and Azide free
Description du produit
Mouse monoclonal [101-1D2] antibody to ICAM3.
Spécificité
This antibody recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (WS: IV V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC, cytotoxicity or proliferation induced by mitogens. It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50. This MAb is excellent for staining of formalin/paraffin tissues.
Applications
Flow Cytometry, IF, IHC-P
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Stimulated human leukocytes.
Hôte
Mouse
Clonalité
Monoclonal
Clone
101-1D2
Isotype
IgG2a
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
110-160 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-ICAM3 Antibody [101-1D2] (A248909).
Synonymes
CD50, CDW 50, CDw50, ICAM 3, ICAM-3, ICAM-R, ICAM3_HUMAN, ICAMR, Intercellular adhesion molecule 3
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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