Anti-HLA DRA Antibody [169-1B5.2] - BSA and Azide free (A252028)

Anti-HLA DRA Antibody [169-1B5.2] - BSA and Azide free

Mouse monoclonal [169-1B5.2] antibody to HLA DRA.

This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human, Bovine, Feline

Human peripheral blood leukocytes.

Mouse

Monoclonal

169-1B5.2

IgG2b

Protein A/G chromatography.

1 mg/ml

36 kDa (alpha chain) / 27 kDa (beta chain)

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-HLA DRA Antibody [169-1B5.2] (A248848).