Anti-HDAC3 Anticorps [PCRP-HDAC3-2D4] (A277838)

Anticorps monoclonal [PCRP-HDAC3-2D4] de souris contre HDAC3 pour ELISA, IP, Flow Cytometry et IF.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-HDAC3 Antibody [PCRP-HDAC3-2D4]
Description du produit
Mouse monoclonal [PCRP-HDAC3-2D4] antibody to HDAC3.
Spécificité
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3, all of which are related to the yeast transcriptional factor Rpd3p, have been identified as histone deacetylases.
Applications
ELISA, IP, Flow Cytometry, IF
Recommander des dilutions
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human HDAC3 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-HDAC3-2D4
Isotype
IgG2b
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
49 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HDAC3 Antibody [PCRP-HDAC3-2D4] - BSA and Azide free (A278426).
Synonymes
HD3, HDAC 3, HDAC3_HUMAN, Histone deacetylase 3, RPD3, RPD3 2, RPD3-2, SMAP45
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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