Spécificité
This antibody recognises Histone deacetylase 1 also known as HDAC1. Histone deacetylases are chromatin-modifying enzymes that are involved in regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. Class I HDACs, which include HDAC1, 2, 3 and 8 are ubiquitously expressed in all tissues and have predominantly nuclear localization.